{"id":1306,"date":"2023-11-12T23:51:18","date_gmt":"2023-11-12T23:51:18","guid":{"rendered":"https:\/\/economicherald.net\/?p=1306"},"modified":"2023-11-12T23:51:18","modified_gmt":"2023-11-12T23:51:18","slug":"argenica-gets-cash-boost-ahead-of-critical-phase-2-clinical-trial","status":"publish","type":"post","link":"https:\/\/economicherald.net\/?p=1306","title":{"rendered":"Argenica gets cash boost ahead of critical Phase 2 clinical trial"},"content":{"rendered":"<p>Argenica receives $2.089 million via R&amp;D Tax Incentive Program to continue developing its ARG-007 lead drug<br \/>\nFunds will be invested in upcoming Phase 2 clinical trial on ischaemic stroke patients<br \/>\nHospitals across all major Australian cities confirmed to be participating in the double-blind study<\/p>\n<p>\u00a0<\/p>\n<p><strong><em>Special Report<\/em>: Argenica Therapeutics has received a R&amp;D cash rebate of almost $2.1 million, which can be applied to further developing ARG-007, including investing back into the upcoming Phase 2 clinical trial on ischaemic stroke patients.<\/strong><\/p>\n<p>Perth-based <a href=\"https:\/\/stockhead.com.au\/company\/argenica-therapeutics-agn\/\">Argenica Therapeutics (ASX: AGN)<\/a> is developing novel therapeutics to reduce brain tissue death after stroke, other types of brain injury, and neurodegenerative diseases.<\/p>\n<p>Argenica\u2019s lead neuroprotective peptide candidate ARG-007 has already successfully demonstrated improved outcomes in pre-clinical stroke models, traumatic brain injury (TBI) and hypoxic ischaemic encephalopathy (HIE).<\/p>\n<p>The ~$2.1m received from the Australian Government\u2019s R&amp;D Tax Incentive Program will be used to continue development of ARG-007. The company was recently given the green light to undertake the Phase 2 \u201cproof of concept\u201d clinical trial of its lead drug for acute ischaemic stroke patients.<\/p>\n<p>Major hospitals in WA, South Australia, VIC, NSW and QLD have all confirmed their participation in the upcoming trial with site governance due to be completed later this quarter.<\/p>\n<p>Eligible patients will receive either a single intravenous dose of ARG-007 or saline placebo prior to undergoing a thrombectomy procedure. The trial will be completed as a double-blind study.<\/p>\n<p>\u00a0<\/p>\n<h2><strong>\u2018<\/strong><strong>Vital for supporting Australian innovation\u2019<\/strong><strong>\u00a0<\/strong><\/h2>\n<p>An \u201cadvance and overseas\u201d finding has also been approved by AusIndustry, enabling both domestic and overseas expenditure on Argenica\u2019s planned pre-clinical efficacy, non-clinical studies, manufacturing, regulatory activities and Phase 2 clinical trial requirements to be included as eligible R&amp;D expenditure for the next three financial years.<\/p>\n<p>Argenica managing director Dr Liz Dallimore said the R&amp;D Tax Incentive Program was vital for supporting Australian innovation.<\/p>\n<p>\u201cThese funds will be applied to further developing the company\u2019s lead neuroprotective peptide candidate, ARG-007, including an upcoming Phase 2 clinical trial in ischaemic stroke patients, as well as continuing to generate pre-clinical data in other neurological conditions, including in TBI, HIE and Alzheimer\u2019s Disease,\u201d she said.<\/p>\n<p>The recently completed Phase 1 clinical trial in healthy human volunteers assessed the safety and tolerability of a single dose of ARG-007<\/p>\n<p>Pre-clinical data has also shown ARG-007 inhibits another of the main abnormal proteins which causes Alzheimer\u2019s Disease.<\/p>\n<p>\u00a0<\/p>\n\n<p>\u00a0<\/p>\n<p><em>This article was developed in collaboration with Argenica Therapeutics, a Stockhead advertiser at the time of publishing.<\/em><\/p>\n<p>\u00a0<\/p>\n<p><em>This article does not constitute financial product advice. You should consider obtaining independent advice before making any financial decisions.<\/em><\/p>\n<p><span class=\"et_bloom_bottom_trigger\"><\/span><\/p>\n<p>The post <a href=\"https:\/\/stockhead.com.au\/health\/argenica-gets-cash-boost-ahead-of-critical-phase-2-clinical-trial\/\">Argenica gets cash boost ahead of critical Phase 2 clinical trial<\/a> appeared first on <a href=\"https:\/\/stockhead.com.au\/\">Stockhead<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Argenica receives $2.089 million via R&amp;D Tax Incentive Program to continue developing its ARG-007 lead drug Funds will be invested in upcoming Phase 2 clinical <a href=\"https:\/\/economicherald.net\/?p=1306\" class=\"read-more-link\">[more&#8230;]<\/a><\/p>\n","protected":false},"author":0,"featured_media":1307,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-1306","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-finance"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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