{"id":1122,"date":"2023-11-07T01:17:37","date_gmt":"2023-11-07T01:17:37","guid":{"rendered":"https:\/\/economicherald.net\/?p=1122"},"modified":"2023-11-07T01:17:37","modified_gmt":"2023-11-07T01:17:37","slug":"asx-health-stocks-clarity-pharma-island-pharma-set-to-embark-on-next-steps-of-clinical-trials","status":"publish","type":"post","link":"https:\/\/economicherald.net\/?p=1122","title":{"rendered":"ASX Health Stocks: Clarity Pharma, Island Pharma set to embark on next steps of clinical trials"},"content":{"rendered":"<p>Clarity Pharma says 50 patients have been imaged at SABRE trial<br \/>\nIsland Pharma granted human research ethics approval for ISLA-101<\/p>\n<p>\u00a0<\/p>\n<h2>Clarity Pharma imaged 50 patients<\/h2>\n<p><strong><a href=\"https:\/\/stockhead.com.au\/company\/clarity-pharmaceuticals-cu6\/\">Clarity Pharmaceuticals (ASX:CU6)<\/a><\/strong> announced that 50 patients have now been imaged with <strong>64Cu-SAR-Bombesin<\/strong> in its US-based diagnostic trial,<strong> SABRE,<\/strong> for participants with <strong>PSMA-negative prostate cancer<\/strong>.<\/p>\n<p>SABRE, which derives from <em>\u201cCopper-64 SAR-BisPSMA in Biochemical Recurrence of prostate cancer<\/em>\u201d is a <strong>Phase II Positron Emission Tomography (PET)<\/strong> imaging trial of participants with PSMA-negative biochemical recurrence (BCR) of prostate cancer following definitive therapy.<\/p>\n<p>The primary objectives of the trial are to investigate the safety and tolerability of the product, as well as its ability to correctly detect recurrence of prostate cancer.<\/p>\n<p><strong>Andrei Iagaru,<\/strong> the Lead Principal Investigator for the trial, said that being able to visualise the gastrin-releasing peptide receptor (GRPr) expressing lesions with SAR-Bombesin has the potential to change the entire treatment paradigm for patients.<\/p>\n<p>\u201cWith more tools to detect prostate cancer that may not be visible with other imaging agents, we may be able to better diagnose and offer more effective treatment for their disease,\u201d he said.<\/p>\n<p>Unique to Clarity\u2019s SAR Technology is the ability to image patients at later timepoints due to the optimal half-life of 64Cu.<\/p>\n<p>\u201cAs such, 64Cu-SAR-Bombesin enables imaging not only on the day of product administration, but also at later timepoints, which may add utility to the diagnosis of cancerous lesions,\u201d Iagaru added.<\/p>\n<p>\u00a0<\/p>\n<h2>Island Pharma granted ethics approval<\/h2>\n<p>Meanwhile, <strong><a href=\"https:\/\/stockhead.com.au\/company\/island-pharmaceuticals-ila\/\">Island Pharmaceuticals (ASX:ILA)<\/a><\/strong> has just been granted <strong>human research ethics approval<\/strong> to commence its <strong>ISLA-101 Single Ascending Dose<\/strong> study, to be performed at <em>Scientia Clinical Research<\/em>\u2019s trial facilities in Sydney.<\/p>\n<p>The Human Research Ethics Committee (HREC) approval was given to commence the dosing of ISLA-101, a drug candidate being repurposed for the prevention and treatment of dengue and other mosquito (or vector) borne diseases.<\/p>\n<p>The study will be a dose escalation study, in which three cohorts of healthy subjects will receive escalating doses of ISLA-101.<\/p>\n<p>The aim is to ensure that administered doses could safely achieve blood concentrations of ISLA-101 that are predicted to be effective against the dengue virus.<\/p>\n<p>Recruitment and dosing will commence imminently, with the data readout expected in early 2024.<\/p>\n<p>\u201cIf all runs smoothly, our aim is to have final data by early 2024 and then rapidly transition to the Phase 2 PEACH study soon thereafter,\u201d said Island CEO, Dr David Foster.<\/p>\n<p>\u00a0<\/p>\n<h2>Clarity and Island Pharma share prices today:<\/h2>\n<p>\u00a0<\/p>\n\n<p><span class=\"mce_SELRES_start\">\ufeff<\/span><span class=\"mce_SELRES_start\"><\/span>\u00a0<br \/>\n<span class=\"et_bloom_bottom_trigger\"><\/span><\/p>\n<p>The post <a href=\"https:\/\/stockhead.com.au\/health\/asx-health-stocks-clarity-pharma-island-pharma-set-to-embark-on-next-steps-of-clinical-trials\/\">ASX Health Stocks: Clarity Pharma, Island Pharma set to embark on next steps of clinical trials<\/a> appeared first on <a href=\"https:\/\/stockhead.com.au\/\">Stockhead<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>Clarity Pharma says 50 patients have been imaged at SABRE trial Island Pharma granted human research ethics approval for ISLA-101 \u00a0 Clarity Pharma imaged 50 <a href=\"https:\/\/economicherald.net\/?p=1122\" class=\"read-more-link\">[more&#8230;]<\/a><\/p>\n","protected":false},"author":0,"featured_media":1123,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-1122","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-finance"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ASX Health Stocks: Clarity Pharma, Island Pharma set to embark on next steps of clinical trials - Economic Herald<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/economicherald.net\/?p=1122\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ASX Health Stocks: 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